Heart disease often presents differently in women than in men, which can delay diagnosis and treatment. While men typically experience classic chest pain, women may have subtler symptoms such as shortness of breath, fatigue, nausea, dizziness, or pain in the jaw, neck, or back. Hormonal changes, especially after menopause, can increase risk by affecting cholesterol, blood pressure, and blood vessel health. Women are also more likely to develop microvascular disease, which affects smaller heart arteries and may not show on standard tests. Awareness of these differences and timely medical evaluation are essential for effective prevention and treatment.