To eliminate the pain of frozen shoulder or rotator cuff injuries and to regenerate the joint, especially with osteo-arthritic elements; acupuncture and Prolozone injection therapy are my treatment protocols. Each component of Prolozone therapy has a specific biological purpose. Procaine acts to re-establish cellular membrane potentials. Anti-inflammatory agents decrease edema and swelling. The inclusion of vitamins and minerals provides necessary substrates of oxygen utilization that in damaged tissues are often deficient. And finally, oxygen utilization is directly stimulated by ozone. It is excellent for all forms of musculo-skeletal and joint pain.