Processed food, sedentary lives, lack of sleep, unceasing stress, dissolving relationships, and collapse of purpose take a massive toll on our health and enjoyment from life. Most healthcare costs are linked to lifestyle-related diseases and nearly all top causes of death are due to chronic conditions. Lifestyle medicine combines an acknowledgment of these facts with evidence that lifestyle interventions such as nutrition, physical activity, sleep, stress reduction, and smoking cessation can prevent, manage, and reverse disease. Using evidence-based medical assessments and leveraging personal health coaching, lifestyle medicine can help people take control of their health and optimize long-term vitality.